Acute and Chronic Therapies in Pediatric Inflammatory Central Nervous System Diseases

Author:

Wilbur Colin1,Yeh E.12

Affiliation:

1. Division of Neurology, Department of Pediatrics, University of Toronto, Hospital for Sick Children, Toronto, Ontario, Canada

2. Department of Neurosciences and Mental Health, SickKids Research Institute, Toronto, Ontario, Canada

Abstract

AbstractRecognition of pediatric neuroinflammatory disorders has increased in recent years, together with an increased knowledge of the immune mechanisms underlying these disorders. These insights have led to paying greater attention to the classification of these disorders, and importantly, increasing information on therapeutic interventions that may improve outcomes. Furthermore, this has occurred in the wake of the development of multiple targeted immune therapies, thus creating a complex treatment landscape. This review aims to summarize the available literature regarding acute and chronic therapies for pediatric inflammatory central nervous system (CNS) disorders. A standardized approach to the initial management of these diseases is presented.

Publisher

Georg Thieme Verlag KG

Subject

Clinical Neurology,Pediatrics, Perinatology, and Child Health

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