Palladium-Catalyzed Regioselective Heck–Suzuki–Miyaura Cascade Cyclization for the Synthesis of Trisubstituted Arylideneisoquinolinones-Reference-Cited by-同舟云学术

Palladium-Catalyzed Regioselective Heck–Suzuki–Miyaura Cascade Cyclization for the Synthesis of Trisubstituted Arylideneisoquinolinones

Published:2019-04-18 Issue:09 Volume:30 Page:1073-1076
ISSN:0936-5214
Container-title:Synlett
language:en
Short-container-title:Synlett

Author:

Asgari M.¹,Mirzazadeh R.²,Larijani B.³,Rashidi Ranjbar P.¹,Rahimi R.⁴,Mahdavi M.³

Affiliation:

1. School of Chemistry, University College of Chemistry, University of Tehran

2. Biochemistry Department, Pasteur Institute of Iran

3. Department of Medicinal chemistry, Facaulty of Pharmacy and Pharmaceutical Sciences Research Center, Tehran University of Medicinal Sciences

4. Department of Chemistry, Iran University of Science and Technology

Abstract

An Ugi four-component reaction was used to construct propargylamide starting materials for a subsequent domino Heck–Suzuki–Miyaura cross-coupling reaction to give derivatives of 4-benzylidene-1-oxo-3,4-dihydro-1H-isoquinoline.

Publisher

Georg Thieme Verlag KG

Subject

Organic Chemistry

Link

http://www.thieme-connect.de/products/ejournals/pdf/10.1055/s-0037-1611804.pdf

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1. Propargyl Amines: Versatile Building Blocks in Post‐Ugi Transformations;ChemistryOpen;2023-01-31

2. Stereoselective Domino Heck‐Suzuki Reactions;European Journal of Organic Chemistry;2022-12-30

3. Annulation of the Ugi Products Using Palladium Catalysts;ChemistrySelect;2022-07-26

4. Comprehensive Strategies for the Synthesis of Isoquinolines: Progress Since 2008;Advanced Synthesis & Catalysis;2020-09-02

5. Palladium-catalyzed regio- and stereoselective synthesis of aryl and 3-indolyl-substituted 4-methylene-3,4-dihydroisoquinolin-1(2H)-ones;Beilstein Journal of Organic Chemistry;2020-05-20