Rhodium(III)-Catalyzed C–H Activation/Alkylation of Diazabicyclic Olefins with Aryl Ketones: Facile Synthesis of Functionalized Cyclopentenes-Reference-Cited by-同舟云学术

Rhodium(III)-Catalyzed C–H Activation/Alkylation of Diazabicyclic Olefins with Aryl Ketones: Facile Synthesis of Functionalized Cyclopentenes

Published:2018-08-23 Issue:15 Volume:29 Page:2023-2026
ISSN:0936-5214
Container-title:Synlett
language:en
Short-container-title:Synlett

Author:

Radhakrishnan K.¹²^ORCID,Santhini P.¹²,Gopalan Greeshma¹²,Smrithy A.¹

Affiliation:

1. Organic Chemistry Section, National Institute for Interdisciplinary Science and Technology (CSIR)

2. Academy of Scientific and Innovative Research (AcSIR)

Abstract

A facile synthesis of biologically important trans-functionalized cyclopentenes by a mild Rh(III)-catalyzed alkylation of strained diazabicyclic olefins with aryl ketones in the presence of ammonium acetate has been developed. The reaction proceeds through C–H bond activation of the aryl ketone groups by transforming them in to an autocleavable directing group, such as in situ-formed imine.

Publisher

Georg Thieme Verlag KG

Subject

Organic Chemistry

Link

http://www.thieme-connect.de/products/ejournals/pdf/10.1055/s-0037-1610654.pdf

Cited by 5 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. γ-CF₃-Allenamides versus 3-CF₃-Cyclopentenylamines: Substituent-Controlled Divergent Reaction of β-CF₃-1,3-Enynamides with β-Dicarbonyl Compounds;The Journal of Organic Chemistry;2024-09-10

2. Variability of Rhodium(III)-Catalyzed Reactions of Aromatic Oximes with Alkenes;Synlett;2020-04-24

3. Transition metal-catalyzed coupling of heterocyclic alkenes via C–H functionalization: recent trends and applications;Organic Chemistry Frontiers;2020

4. An Enantioselective Cp x Rh(III)‐Catalyzed C−H Functionalization/Ring‐Opening Route to Chiral Cyclopentenylamines;Angewandte Chemie International Edition;2019-02-18

5. An Enantioselective Cpx Rh(III)-Catalyzed C−H Functionalization/Ring-Opening Route to Chiral Cyclopentenylamines;Angewandte Chemie;2019-01-25