Ph3P/I–-Promoted Dichlorination or Dibromination of Epoxides with XCH2CH2X (X = Cl or Br)-Reference-Cited by-同舟云学术

Ph3P/I–-Promoted Dichlorination or Dibromination of Epoxides with XCH2CH2X (X = Cl or Br)

Published:2018-12-19 Issue:02 Volume:30 Page:181-184
ISSN:0936-5214
Container-title:Synlett
language:en
Short-container-title:Synlett

Author:

Lin Jin-Hong¹,Zheng Xing²,Xiao Ji-Chang¹,Long Jin²¹,Chen Jia¹,Li Rong²,Liu Zhuo²¹,Xiao Xuan²¹

Affiliation:

1. Key Laboratory of Organofluorine Chemistry, Shanghai Institute of Organic Chemistry, University of Chinese Academy of Sciences, Chinese Academy of Sciences

2. Institute of Pharmacy and Pharmacology, Hunan Province Cooperative Innovation Center for Molecular Target New Drug Study, University of South China

Abstract

Ph3P/I–-promoted dichlorination and dibromination of epoxides by using XCH2CH2X (X = Cl or Br) as the halogen source and reaction solvent is described. All reagents are widely available and easy to handle, and mild conditions and operational simplicity make this protocol attractive.

Funder

National Natural Science Foundation of China

Chinese Academy of Sciences

Publisher

Georg Thieme Verlag KG

Subject

Organic Chemistry

Link

http://www.thieme-connect.de/products/ejournals/pdf/10.1055/s-0037-1610308.pdf

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