Affiliation:
1. School of Science and Technology, Chemistry Division, Università di Camerino
Abstract
This review article summarizes the fundamental synthetic procedures aimed at the preparation of unsymmetrical bisindolylmethanes that have appeared in the literature since 2010. To this goal, reactive electrophilic indole-containing intermediates are mostly generated from indolylmethanols, indolylmethanamines, and indolylmethanthio derivatives and then made to react with simple or functionalized indoles. The asymmetric synthesis of bisindolylmethanes can be also achieved under chiral-catalyzed conditions.1 Introduction2 Direct Three-Component Coupling3 Reaction of Indolylmethanols4 Reaction of Indolylmethanamine Derivatives5 Reaction of 3-Vinylindoles6 Reaction of indolylmethanthio Derivatives7 Bisindolylmethanes by Ring Closure of Alkyne Derivatives8 Miscellaneous Methods9 Conclusion
Subject
Organic Chemistry,Catalysis
Cited by
38 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献