KI-Promoted Oxidative Coupling of Styrenes with Indoles under Metal-Free Conditions: Facile Access to C-3 Dicarbonyl Indoles-Reference-Cited by-同舟云学术

KI-Promoted Oxidative Coupling of Styrenes with Indoles under Metal-Free Conditions: Facile Access to C-3 Dicarbonyl Indoles

Published:2019-07-11 Issue:18 Volume:51 Page:3511-3519
ISSN:0039-7881
Container-title:Synthesis
language:en
Short-container-title:Synthesis

Author:

Zhou Bochao¹,Guo Shiyu¹,Fang Zheng¹,Yang Zhao²,Liu Chengkou¹,He Wei¹,Zhu Ning¹,Li Xin¹,Guo Kai¹³

Affiliation:

1. College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University

2. School of Engineering, China Pharmaceutical University

3. State Key Laboratory of Materials-Oriented Chemical Engineering, Nanjing Tech University

Abstract

A new and efficient method for the synthesis of C-3 dicarbonyl indoles via oxidative cross-coupling of styrenes with indoles under metal-free conditions has been developed. Moreover, a broad scope of C-3 dicarbonyl indoles in moderate to good yields were obtained, and a plausible mechanism is proposed based on control and isotope-labeling experiments.

Funder

National Natural Science Foundation of China

Publisher

Georg Thieme Verlag KG

Subject

Organic Chemistry,Catalysis

Link

http://www.thieme-connect.de/products/ejournals/pdf/10.1055/s-0037-1611888.pdf

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