Enantioselective Bromolactonization of Deactivated Olefinic Acids: Studies Toward the Synthesis of Brominated Isochroman-1,4-diones-Reference-Cited by-同舟云学术

Enantioselective Bromolactonization of Deactivated Olefinic Acids: Studies Toward the Synthesis of Brominated Isochroman-1,4-diones

Published:2018-10 Issue:04 Volume:02 Page:0293-0297
ISSN:2509-9396
Container-title:SynOpen
language:en
Short-container-title:SynOpen

Author:

Li Danqing¹,He Hailong²,Huang Xiaodan²,Yu Pei³,Jiang Xiaojian³^ORCID

Affiliation:

1. First Affiliated Hospital of Guangzhou University of Traditional Chinese Medicine

2. Guangzhou Wanglaoji Pharmaceutical Company Limited

3. Institute of New Drug Research and Guangzhou Key Laboratory of Innovative Chemical Drug Research in Cardiocerebrovascular Diseases, Jinan University College of Pharmacy

Abstract

Enantioselective bromolactonization using an amino-carbamate catalyst to generate brominated isochroman-1,4-diones is described. Excellent yields and moderate enantioselectivities were achieved.

Funder

Natural Science Foundation of Guangdong Province

Fundamental Research Funds for the Central University

Publisher

Georg Thieme Verlag KG

Subject

Organic Chemistry,Materials Science (miscellaneous),Biomaterials,Catalysis

Link

http://www.thieme-connect.de/products/ejournals/pdf/10.1055/s-0037-1610401.pdf

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