Niobium Pentachloride Mediated (Hetero)aromatic Aldehyde Friedel–Crafts Hydroxyalkylation with Arenes: An Efficient Strategy to Synthesize Triarylmethanes-Reference-Cited by-同舟云学术

Niobium Pentachloride Mediated (Hetero)aromatic Aldehyde Friedel–Crafts Hydroxyalkylation with Arenes: An Efficient Strategy to Synthesize Triarylmethanes

Published:2019-08-29 Issue:23 Volume:51 Page:4498-4506
ISSN:0039-7881
Container-title:Synthesis
language:en
Short-container-title:Synthesis

Author:

Rodrigues Shirley M. M.¹,Previdi Daniel,Baviera Giovanni S.,Matias Alexandre A.,Donate Paulo M.

Affiliation:

1. Departamento de Química, Faculdade de Filosofia, Ciências e Letras de Ribeirão Preto, Universidade de São Paulo

Abstract

Niobium pentachloride is an efficient and useful Lewis acid to conduct Friedel–Crafts hydroxyalkylation between arenes and (hetero)aromatic aldehydes, to generate triarylmethanes. This practical methodology offers several advantages, such as short reaction time, mild experimental conditions, and excellent yields.

Funder

Fundação de Amparo à Pesquisa do Estado de São Paulo

Publisher

Georg Thieme Verlag KG

Subject

Organic Chemistry,Catalysis

Link

http://www.thieme-connect.de/products/ejournals/pdf/10.1055/s-0037-1610727.pdf

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