Regioselective Construction of Coumarin-1,2,4-triazines via a Cs2CO3-Catalyzed [3+3] Cycloaddition Reaction-Reference-Cited by-同舟云学术

Regioselective Construction of Coumarin-1,2,4-triazines via a Cs2CO3-Catalyzed [3+3] Cycloaddition Reaction

Published:2022-04-19 Issue:11 Volume:33 Page:1097-1101
ISSN:0936-5214
Container-title:Synlett
language:en
Short-container-title:Synlett

Author:

Zhang Fa-Guang¹^ORCID,Ma Jun-An¹²,Liu Xuan-Yu¹

Affiliation:

1. Department of Chemistry, Tianjin Key Laboratory of Molecular Optoelectronic Sciences, Frontiers Science Center for Synthetic Biology (Ministry of Education), and Tianjin Collaborative Innovation Centre of Chemical Science & Engineering, Tianjin University

2. Joint School of National University of Singapore and Tianjin University, International Campus of Tianjin University

Abstract

AbstractA cesium carbonate (Cs2CO3)-catalyzed [3+3] cycloaddition reaction of coumarin-diazo reagents with glycine imino esters is established to produce tetrahydro-1,2,4-triazines in good yields with excellent regioselectivity. One-pot cycloaddition/oxidation protocol could further provide practical access to a series of new coumarin-decorated 1,2,4-triazines.

Funder

National Key Research and Development Program of China

National Natural Science Foundation of China

Publisher

Georg Thieme Verlag KG

Subject

Organic Chemistry

Link

http://www.thieme-connect.de/products/ejournals/pdf/10.1055/a-1828-7504.pdf

Reference2 articles.

1. Silver‐Catalyzed [3+2] Cycloaddition Approach to Coumarin‐Decorated Tetrazoles

2. Highly substituted pyridines via tethered imine–enamine (TIE) methodology

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