Subependymomas – Characteristics of a “Leave me Alone” Lesion

Author:

Kammerer Sara1,Mueller-Eschner Monika1,Lauer Arne1,Luger Anna-Luisa2,Quick-Weller Johanna3,Franz Kea3,Harter Patrick4,Berkefeld Joachim1,Wagner Marlies1

Affiliation:

1. Goethe-University, Institute for Neuroradiology, Frankfurt, Germany

2. Goethe-University, Department of Neurology, Frankfurt, Germany

3. Goethe-University, Department of Neurosurgery, Frankfurt, Germany

4. Edinger Institute, Goethe University, Department of Neurology, Frankfurt, Germany

Abstract

Purpose Intracranial subependymomas are rare, mostly asymptomatic tumours, which are often found incidentally and therefore did not receive much attention in previous literature. By being classified as benign grade I in the WHO classification of tumours of the central nervous system, they are given a special status compared to the other ependymal tumours. Tumor recurrences are a rarity, spinal “drop metastases” do not occur. While etiological, pathological and therapeutic characteristics have been subject of several publications over the last few decades and have meanwhile been well studied, the imaging characteristics are much less well received. Material and method Retrospective analysis of our relatively large group of 33 patients with subependymoma, including 4 patients with a mixture of subependymomas with ependymal cell fractions in terms of imaging and clinical aspects and with reference to a current literature review. Results Subependymomas have typical image morphologic characteristics that differentiate them from tumors of other entities, however, the rare subgroup of histopathological mixtures of subependymomas with ependymal cell fractions has no distinctly different imaging properties. Conclusions Knowing the imaging characteristics of subpendymoma and their differential diagnoses is of particular importance in order to be able to decide between the necessity of follow-up controls, an early invasive diagnosis or, depending on the entity, tumor resection. Key Points:  Citation Format

Publisher

Georg Thieme Verlag KG

Subject

Radiology Nuclear Medicine and imaging

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