Efficient Metal-Free Synthesis of Heterotriarylmethanes by 1,4-Addition of Benzofuran Azadienes-Reference-Cited by-同舟云学术

Efficient Metal-Free Synthesis of Heterotriarylmethanes by 1,4-Addition of Benzofuran Azadienes

Published:2024-07-22 Issue: Volume: Page:
ISSN:0936-5214
Container-title:Synlett
language:en
Short-container-title:Synlett

Author:

Huang Hong-Li¹,Peng Zhongzhong²,Gao Fei³,Li Shan¹,Lv Yong-Zheng¹,Shi Ya-Qian¹,Liu Chang-Bo⁴

Affiliation:

1. College of Chemistry and Chemical Engineering, Liaocheng University

2. Ningbo Hangzhou Bay Hospital

3. Institute of Translation Medicine, Shanghai University

4. Liuyuan Street Office of Dongchangfu District

Abstract

AbstractA novel and efficient method has been established for synthesizing a variety of heterotriarylmethanes with good yields by employing a metal-free self-coupling reaction of benzofuran azadienes. The involvement of t-BuONa is essential in this process. Remarkably, this technique boasts mild reaction conditions and exceptional compatibility with various functional groups, rendering it a versatile and invaluable asset in the realm of organic synthesis.

Funder

Natural Science Foundation of Shandong Province

Liaocheng University

National Natural Science Foundation of Shanghai

Publisher

Georg Thieme Verlag KG

Link

http://www.thieme-connect.de/products/ejournals/pdf/10.1055/a-2370-6462.pdf

Reference26 articles.

1. Structure–Activity Relationship of Benzofuran Derivatives with Potential Anticancer Activity

2. Benzofuran derivatives and their anti-tubercular, anti-bacterial activities

3. Palladium-Catalyzed Selective Heck-Type Diarylation of Allylic Esters with Aryl Halides Involving a β-OAc Elimination Process

4. Synthesis of Functionalized Benzo[b]furans via Oxidative Cyclization of o-Cinnamyl Phenols

5. One-pot synthesis of 2,3-disubstituted benzofurans from 2-chlorophenols using palladium–dihydroxyterphenylphosphine catalyst