Pulmonary Aspergillosis in People with Cystic Fibrosis

Author:

Schwarz C.12,Eschenhagen P.N.12,Mainz J.G.34,Schmidergall T.12,Schuette H.5,Romanowska E.12

Affiliation:

1. HMU-Health and Medical University, Potsdam, Germany

2. Division Cystic Fibrosis, Clinic Westbrandenburg, Potsdam, Germany

3. Department of Paediatric Pneumology, Allergology, Cystic Fibrosis Center, Klinikum Westbrandenburg, Brandenburg a. d. Havel, Germany

4. University Hospital of the Brandenburg Medical School, Brandenburg a. d. Havel, Germany

5. Pneumology and Respiratory Medicine, Ernst von Bergmann Klinikum, Potsdam, Germany

Abstract

AbstractIn the last decade, fungal respiratory diseases have been increasingly investigated for their impact on the clinical course of people with cystic fibrosis (CF), with a particular focus on infections caused by Aspergillus spp. The most common organisms from this genus detected from respiratory cultures are Aspergillus fumigatus and Aspergillus terreus, followed by Aspergillus flavus, Aspergillus niger, and Aspergillus nidulans. These species have been identified to be both chronic colonizers and sources of active infection and may negatively impact lung function in people with CF. This review article discusses definitions of aspergillosis, challenges in clinical practice, and current literature available for laboratory findings, clinical diagnosis, and treatment options for pulmonary diseases caused by Aspergillus spp. in people with CF.

Publisher

Georg Thieme Verlag KG

Cited by 1 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. The Spectrum of Pulmonary Aspergillosis;Seminars in Respiratory and Critical Care Medicine;2024-01-29

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