Reperfusion therapy for acute ischemic stroke: where are we in 2023?

Author:

Martins Sheila Cristina Ouriques12ORCID,Pontes-Neto Octávio Marques3ORCID,Pille Arthur12ORCID,Secchi Thaís Leite2ORCID,Miranda Alves Maramélia Araújo de4ORCID,Rebello Letícia Costa5ORCID,Oliveira-Filho Jamary6ORCID,Lange Marcos Christiano7ORCID,de Freitas Gabriel R.8ORCID,de Andrade João Brainer Clares4ORCID,Rocha Letícia Januzi de Almeida9ORCID,Bezerra Daniel da Cruz10ORCID,Souza Ana Claudia de2ORCID,Carbonera Leonardo Augusto2ORCID,Nogueira Raul Gomes11ORCID,Silva Gisele Sampaio4ORCID

Affiliation:

1. Universidade Federal do Rio Grande do Sul, Hospital de Clínicas de Porto Alegre, Porto Alegre RS, Brazil.

2. Hospital Moinhos de Vento, Porto Alegre RS, Brazil.

3. Universidade de São Paulo, Faculdade de Medicina de Ribeirão Preto, Ribeirão Preto SP, Brazil.

4. Universidade Federal de São Paulo, Hospital São Paulo, São Paulo SP, Brazil.

5. Hospital de Base de Brasília, Brasília DF, Brazil.

6. Universidade Federal da Bahia, Salvador BA, Brazil.

7. Universidade Federal do Paraná, Hospital de Clínicas, Curitiba PR, Brazil.

8. Hospital Quinta D'Or, Rio de Janeiro RJ, Brazil.

9. Hospital Universitário Professor Alberto Antunes, Maceió AL, Brazil.

10. Hospital Pró-Cardíaco, Rio de Janeiro RJ, Brazil.

11. University of Pittsburgh, Pittsburgh PA, United States.

Abstract

AbstractOver the last three decades, stroke care has undergone significant transformations mainly driven by the introduction of reperfusion therapy and the organization of systems of care. Patients receiving treatment through a well-structured stroke service have a much higher chance of favorable outcomes, thereby decreasing both disability and mortality. In this article, we reviewed the scientific evidence for stroke reperfusion therapy, including thrombolysis and thrombectomy, and its implementation in the public health system in Brazil.

Publisher

Georg Thieme Verlag KG

Subject

Neurology,Neurology (clinical)

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