Severe Depressive Episode with Psychotic Symptoms: A Homoeopathic Case Study

Abstract

Abstract Background Global burden of depression has increased in the recent years with reduction in productivity, reduced quality of life, increased morbidity and mortality. Although there is an evidence base for effectiveness of homoeopathy in depression, severe depressive episode (SDE) with psychotic symptoms is challenging for homoeopaths to treat. Case Summary A 27-year-old female patient presented with dullness, easy fatiguability, withdrawn nature with loathing of life, lack of interest in daily and pleasurable activities. She believed that her body was disfigured and was suspicious that someone was spying on her. The case was diagnosed as SDE with psychotic symptoms (F-32.3 according to International Classification of Diseases, 10th revision). Natrum muriaticum 30 was given as the first prescription and repeated as necessary in the follow-up visits. Carcinosinum 200 was given as intercurrent on the basis of past history of thyroid malignancy. This case presents an example for Hahnemann's concept of Somato-psychic disorder mentioned in §216 of Organon of Medicine. Results Hamilton Depression Rating Scale score at baseline which was 42 turned to 0 at the end of 6 months and remained the same over a 3 year observation period. Conclusion Homoeopathic medicines are effective in the management of SDE with psychotic symptoms. Effectiveness of Natrum muriaticum in reducing depressive symptoms and its effect on neurotransmitters is the arena of future research.