Navigating the Role of Anti-Obesity Agents Prior to Pregnancy: A Narrative Review

Author:

Goldberg Alyse S.1,Dolatabadi Samin2,Dutton Heidi3,Benham Jamie L.4

Affiliation:

1. Department of Medicine, University of Toronto, Toronto, Ontario, Canada

2. Department of Medicine, University of Calgary, Calgary, Canada

3. Department of Medicine, University of Ottawa, Ottawa, Canada

4. Department of Medicine and Community Health Sciences, University of Calgary, Calgary, Canada

Abstract

AbstractUtilization of anti-obesity agents is rising in reproductive-age females with some planning for future pregnancy. Lifestyle-induced weight loss has been shown to increase spontaneous conception rate, improve rates of fertility intervention complications, and decrease pregnancy comorbidities. However, the definitive role of assisting weight loss with medication prior to pregnancy remains to be established. The implications of anti-obesity agent used prior to pregnancy are explored in this narrative review, considering benefits of weight loss as well as available evidence for use and risks of anti-obesity agents prior to pregnancy.

Publisher

Georg Thieme Verlag KG

Subject

Physiology (medical),Obstetrics and Gynecology,Endocrinology,Reproductive Medicine,Endocrinology, Diabetes and Metabolism

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