Pituitary Hormonal Disturbances in Aneurysmal Subarachnoid Hemorrhage-Reference-Cited by-同舟云学术

Pituitary Hormonal Disturbances in Aneurysmal Subarachnoid Hemorrhage

Published:2023-06 Issue:02 Volume:42 Page:e105-e113
ISSN:0103-5355
Container-title:Arquivos Brasileiros de Neurocirurgia: Brazilian Neurosurgery
language:en
Short-container-title:Arquivos Brasileiros de Neurocirurgia: Brazilian Neurosurgery

Author:

Moura Jose Carlos de¹^ORCID,Azevedo Hildo Rocha Cirne de²^ORCID,Valença Marcelo Moraes³^ORCID,Vidal Claudio Henrique Fernandes⁴,Moura Samuel Miranda de⁵^ORCID,Rodrigues Mateus de Sousa⁵⁶^ORCID

Affiliation:

1. Neurosurgery Department, School of Medicine, Universidade Federal do Vale do São Francisco, Petrolina PE, Brazil

2. Neurosurgery Department, Federal University of Pernambuco, Recife, PE, Brazil

3. Neurosurgery Department, University of Pernambuco, Recife, PE, Brazil

4. Neurosurgery Department, Federal University of Pernambuco, Recife, Brazil

5. Neurosurgery Department, Hospital Beneficiência Portuguesa, São Paulo, SP, Brazil

6. Neurosurgery Department, Hospital da Restauração, Recife, PE, Brazil

Abstract

Abstract Objective The objective of the present study was to assess the hormonal alterations that occurred in patients with subarachnoid hemorrhage. Methods This is a case series with 21 patients diagnosed with subarachnoid hemorrhage of aneurysmal etiology up to 30 days after the ictus. The following hormonal measurements were performed in these patients: cortisol, GH, testosterone, prolactin, estradiol, FSH, LH, FSH, T3, T4 and free T4. The hormonal results of the cases were compared with the results of twelve volunteers from the control group and correlated with findings in brain tomography, cerebral angiography, Hunt-Hess scale, and vasospasm. Results The main altered hormones were cortisol (52.6%), GH (42.9%) and TSH (28.6%). There was a trend towards more severe cases in the following groups of patients: Hunt-Hess scale > 2, Fisher scale > 1, aneurysmal topography in the anterior communicating artery and those who had vasospasm. Conclusion The present study observed the tendency of pituitary hormonal changes in patients with subarachnoid hemorrhage of aneurysmal etiology, corroborating the need for dosage of hormones from the hypothalamic-pituitary axis in the management of these cases.

Publisher

Georg Thieme Verlag KG

Subject

Neurology (clinical),Surgery

Link

http://www.thieme-connect.de/products/ejournals/pdf/10.1055/s-0043-1769782.pdf

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