Primary Sarcomas of the Larynx: A Case Series of Four Different Histopathologic Types

Author:

Abu-Dayeh Ala S.1ORCID,Murshed Khaled A.1,Ammar Adham1,Petkar Mahir1ORCID

Affiliation:

1. Division of Anatomic Pathology, Hamad Medical Corporation, Doha 576214, Qatar

Abstract

AbstractPrimary laryngeal sarcomas are rare. Their nomenclature and classification are similar to soft tissue counterparts; however, there are notable differences between clinical presentation, behavior, treatment, and follow-up. There is sparse information regarding the clinical features, biologic behavior, and treatment modalities of laryngeal sarcomas. To increase our understanding about these tumors, we describe herein an additional series of four cases of different pathologic types of laryngeal sarcomas, including low-grade chondrosarcoma, leiomyosarcoma, well-differentiated liposarcoma, and undifferentiated pleomorphic sarcoma. Our main aim is to upsurge awareness about the morphologic variations of laryngeal sarcomas, to avoid potential pitfalls during histopathologic examination. It is essential to ensure that correct diagnosis, subclassification, and grading are achieved for proper guidance of treatment and clinical follow-up at multidisciplinary team meetings.

Publisher

Georg Thieme Verlag KG

Reference18 articles.

1. Primary sarcomas of the larynx: a clinicopathologic study of 27 cases;J M Velez Torres;Head Neck Pathol,2021

2. Laryngeal soft tissue sarcoma: systematic review and individual patient data analysis of 300 cases;A V Ramdulari;Head Neck,2021

3. Sarcomas of the larynx: one institution's experience and treatment protocol analyses;J Astl;Medicina (Kaunas),2021

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