Affiliation:
1. Chemistry Services, Aragen Life Sciences (Formerly known as GVK Biosciences)
2. Department of Engineering Chemistry, Andhra University
Abstract
AbstractWe describe the efficient total syntheses of naturally occurring tripeptides acidiphilamides A–C and epi-acidiphilamides A–C, which were prepared from commercially available l-phenyl alanine using hexafluorophosphate azabenzotriazole tetramethyl uronium (HATU) as peptide coupling reagent. The structures of the natural acidiphilamides A, B and C were characterized by NMR, MS and SOR data, which match those of natural products, whereas the structures of epi-acidiphilamides A, B and C were confirmed by 2D NMR studies.
Subject
Organic Chemistry,Materials Science (miscellaneous),Biomaterials,Catalysis