Affiliation:
1. Department of Diagnostic and Interventional Radiology, Eberhard Karls University Tübingen, Tübingen, Germany
2. Department of Urology, Eberhard Karls University Tübingen, Tübingen, Germany
Abstract
Background Retroperitoneal fibrosis is a rare disease with an incidence of 0–1/100 000 inhabitants per year and is associated with chronic inflammatory fibrosis of the retroperitoneum and the abdominal aorta. This article sheds light on the role of radiological imaging in retroperitoneal fibrosis, names various differential diagnoses and provides an overview of drug and surgical treatment options.
Methods A literature search for the keywords “retroperitoneal fibrosis” and “Ormond’s disease” was carried out in the PubMed database between January 1, 1995 and December 31, 2019 (n = 1806). Mainly original papers were selected, but also reviews, in English and German language, with a focus on publications in the last 10 years, without excluding older publications that the authors believe are relevant to the topic discussed in the review (n = 40).
Results and Conclusion Ormond’s disease is a rare but important differential diagnosis for nonspecific back and flank pain. Imaging diagnostics using CT or MRI show a retroperitoneal mass, which must be differentiated from lymphoma, sarcoma, multiple myeloma and Erdheim-Chester disease. Patients have an excellent prognosis under adequate therapy. FDG-PET/CT or FDG-PET/MRT should be considered as potential modalities, as hybrid imaging can evaluate both the morphological changes and the inflammation.
Key Points:
Citation Format
Subject
Radiology Nuclear Medicine and imaging
Reference40 articles.
1. Retroperitoneal fibrosis;A Vaglio;Lancet,2006
2. Retroperitoneal fibrosis, M. Ormond, periaoartitis, ...?;B Vogt;Ther Umsch,2008
3. [(18)F]-Fluorodeoxyglucose Positron Emission Tomography in the Diagnosis, Treatment Stratification, and Monitoring of Patients with Retroperitoneal Fibrosis: A Prospective Clinical Study;A Fernando;Eur Urol,2017
4. Idiopathic retroperitoneal fibrosis: a review of the pathogenesis and approaches to treatment;R D Swartz;Am J Kidney Dis,2009
5. IgG4-related Retroperitoneal Fibrosis: An Emerging Masquerader With a Sinister Presentation;A Chandna;Urology,2019
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