Affiliation:
1. Woodlands Health Campus, National Healthcare Group,
Singapore
2. Warrington and Halton Hospitals NHS Foundation Trust, Warrington,
United Kingdom
Abstract
AbstractCOVID-19 is a global pandemic with high mortality in vulnerable groups. Given the
current lack of definitive treatment or vaccine that significantly reduces
mortality rate, governments, researchers and healthcare providers are racing to
find possible solutions to the crisis. Vitamin D and its analogues have been
previously studied for their non-skeletal benefits. In particular, questions
regarding their role in the modulation of immunity have re-surfaced, in view of
possible epidemiological links observed between COVID-19 and vitamin D levels in
selected populations. In this review, we highlight potential mechanisms and
summarise the evidence for and against the potential role of vitamin D
supplementation in our fight against COVID-19.
Subject
Biochemistry, medical,Clinical Biochemistry,Endocrinology,Biochemistry,General Medicine,Endocrinology, Diabetes and Metabolism