Affiliation:
1. College of Pharmaceutical Science, Zhejiang University of Technology
2. College of Chemical Engineering, Zhejiang University of Technology
Abstract
AbstractAn effective tandem reaction of 4-aminocoumarins and 1,3-diarylpropenes mediated by Cu(OTf)2/TBHP (tert-butyl hydroperoxide)/O2 that provides various benzopyrano[4,3-b]pyridines in moderate to good yields is disclosed. The reaction proceeds through oxidative coupling, intramolecular cyclization, and dehydro-aromatization. This approach has the advantages of high atom-economy, environmental compatibility, and wide substrate scope.
Funder
National Natural Science Foundation of China
Subject
Organic Chemistry,Catalysis
Cited by
2 articles.
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