Oncological Safety and Feasibility of Posterior Marginal Mandibulectomy vis-à-vis Anterior Marginal Mandibulectomy in Oral Cancers

Author:

Nair Sudhir1,Singhavi Hitesh R.2,Joshi Kamal Deep3ORCID,Shetty Rathan1,Joshi Poonam1,Lashkar Sarbani Ghosh4ORCID,Chaturvedi Pankaj5

Affiliation:

1. Advanced Centre for Treatment, Research and Education in Cancer (ACTREC), Tata Memorial Centre, Affiliated to the Homi Bhabha National Institute, Navi Mumbai, Maharashtra, India

2. Department of Surgical Oncology, Fortis Hospital Mulund, Mumbai, Maharashtra, India

3. Command Hospital (WC), Chandimandir, Haryana, India

4. Department of Radiation Oncology, Tata Memorial Hospital, Affiliated to the Homi Bhabha National Institute, Mumbai, Maharashtra, India

5. Department of Surgical Oncology, Tata Memorial Hospital, Affiliated to the Homi Bhabha National Institute, Mumbai, Maharashtra, India

Abstract

The surgical management of retromolar trigone cancer (RTC) is an area of contention regarding the extent of bony resection. We aim to evaluate the oncological safety and feasibility of posterior marginal mandibulectomy (PMM) for RTC. We analyzed the clinical records of 98 patients with squamous cell carcinoma managed surgically using marginal mandibulectomy during 2014 to 2017, in which anterior segment mandibulectomy (AMM) and PMM were done in 56 and 42 patients, respectively. The median follow-up time was 44.4 months (95% confidence interval [CI] 42.3, 49.5) and the overall survival rate was 93.9% (95% CI 89.4–98.8%). The local recurrence rate was 19.6 and 18.3 % in PMM and AMM (p = 0.854). In the PMM group, osteoradionecrosis (ORN) was detected in two patients (4.3%) and fractures in one (2.1%) patient, while the AMM group neither had fracture nor ORN till the latest follow-up. The study results suggest that PMM is an oncological safe and adequate procedure for RTC.

Publisher

Georg Thieme Verlag KG

Reference14 articles.

1. Diagnostic approach to retromolar trigone cancer by multiplanar computed tomography reconstructions;S Mazziotti;Can Assoc Radiol J,2014

2. Posterior marginal mandibulectomy in the management of cancer of the oral cavity and oropharynx;G J Petruzzelli;Otolaryngol Head Neck Surg,2003

3. Posterior marginal mandibulectomy for cancer of the oral cavity and oropharynx. Experience with 14 clinical cases [in French];V Pinsolle;Ann Chir Plast Esthet,1997

4. Biomechanics of mandibular reconstruction: a review;R CW Wong;Int J Oral Maxillofac Implants,2010

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