Intracranial Solitary Fibrous Tumor with Concurrent Meningioma: Case Report and Review of the Literature

Author:

Gonzales-Portillo Joaquin Vega1ORCID,Showing Marco Gonzales-Portillo2,Tanta Luis A. Huamán3,Zambrano Sandro Casavilca4

Affiliation:

1. Universidad Peruana de Ciencias Aplicadas, Lima, Perú

2. Department of Neurosurgery, Instituto de Neurociencias de Lima, School of Medicine, Universidad Peruana Cayetano Heredia, Clínica San Felipe, Lima, Perú

3. Division of Neurosurgery, Hospital Nacional Dos de Mayo, Lima, Perú

4. Management Unit of the National Tumor Bank, Instituto Nacional de Enfermedades Neoplásicas, Lima, Perú

Abstract

Abstract Introduction The present study describes a case of an intracranial solitary fibrous tumor (iSFT) concurrent with meningioma in different anatomical regions. Case Description A female patient, 64-years-old, presented with an 18-month history of progressive vision impairment in the right eye and no other neurological symptoms. The magnetic resonance imaging (MRI) revealed two solid and expansive lesions: one with right interhemispheric occipital location and dependent on the falx cerebri, and another located in the anterior skull base. We opted for a right frontotemporal craniotomy for the first tumor, and a right occipital craniotomy, 41-days later, for the second one, showing no postoperative complications. Histological and immunohistochemical findings confirmed the diagnosis of a grade-I fibrous meningioma and a grade-III SFT. After 9 months of follow-up, the patient showed vision improvement and no signs of neurological compromise or tumor recurrence in the last MRI. Conclusions The present study describes the first reported case of a patient with an intracranial SFT associated with a meningioma in different anatomical locations. The involved pathogenesis and evolution of both coexisting tumors are still unknown, which highlights the need for more case reports on them.

Publisher

Georg Thieme Verlag KG

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