Renin-Angiotensin-Aldosterone System in the Pathogenesis of Pregnancy-Induced Hypertension

Author:

Świątkowska-Stodulska Renata1,Kmieć Piotr1,Stefańska Katarzyna2,Sworczak Krzysztof1

Affiliation:

1. Department of Endocrinology and Internal Medicine, Medical University of Gdańsk

2. Department of Obstetrics, Medical University of Gdańsk

Abstract

SummaryHypertension occurs in 7–10% of pregnant women. Despite the continuous development of medicine, it is still an important risk factor for perinatal mortality of both mothers and fetuses. Pregnant women with hypertension are at greater risk of complications such as: placental abruption, cerebral and cardiac incidents, multiorgan failure, and disseminated intravascular coagulation. The aim of this review was to discuss multilevel disorders of the renin-angiotensin-aldosterone system in the etiopathogenesis of pregnancy-induced hypertension.

Publisher

Georg Thieme Verlag KG

Subject

Endocrinology,General Medicine,Endocrinology, Diabetes and Metabolism,Internal Medicine

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