Iridium-Catalyzed Formal [4+1] Annulation of Benzamides and Cyclopropanols to Afford Isoindolin-1-one Derivatives via C–H Activation
Author:
Affiliation:
1. West China Hospital, Sichuan University
2. Key Laboratory of Drug-Targeting and Drug Delivery System of the Education Ministry and Department of Medicinal Chemistry, West China School of Pharmacy, Sichuan University
Abstract
Funder
Department of Science and Technology of Sichuan Province
National Natural Science Foundation of China
Publisher
Georg Thieme Verlag KG
Subject
Organic Chemistry,Catalysis
Link
http://www.thieme-connect.de/products/ejournals/pdf/10.1055/a-1780-1935.pdf
Reference5 articles.
1. The medicinal chemist's toolbox for late stage functionalization of drug-like molecules
2. Cobalt(II)‐Catalyzed C−H/N−H Functionalization and Annulation of N ‐(quinolin‐8‐yl)benzamide with Cyclopropanols
3. Rhodium(III)-Catalyzed Coupling of Arenes with Cyclopropanols via C–H Activation and Ring Opening
4. Synthesis of 2-Substituted Quinolines via Rhodium(III)-Catalyzed C-H Activation of Imidamides and Coupling with Cyclopropanols
5. C–H Activation versus Ring Opening and Inner- versus Outer-Sphere Concerted Metalation–Deprotonation in Rh(III)-Catalyzed Oxidative Coupling of Oxime Ether and Cyclopropanol: A Density Functional Theory Study
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1. Rhodium(III)‐Catalyzed [4+1] Oxidative Annulation of Amides with 1,3‐enynes Through 1,4‐Rhodium Migration;Advanced Synthesis & Catalysis;2023-06-02
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