Abstract
AbstractA concise and practical silver-catalyzed nitrogen-atom-transfer protocol was developed to access versatile nitriles from ubiquitous carboxylic acids with N-cyano-N-phenyl-p-toluenesulfonamide. This protocol complements the established carboxylic acids-to-nitriles conversion methods, which suffer from laborious steps, high temperatures (≥200 °C), or limited substrate scopes. This approach operates broadly across diverse aryl, alkenyl, and primary-, secondary-, or tertiary-alkyl carboxylic acids.
Funder
Wuhan University
National Natural Science Foundation of China,
Fundamental Research Funds for the Central Universities
Cited by
1 articles.
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