Affiliation:
1. College of Chemistry and Chemical Engineering, Central South University
2. The Institute for Advanced Studies, Wuhan University
Abstract
AbstractCross-coupling reactions are essential for the synthesis of complex organic molecules. Here, we report a nickel-catalyzed Ullmann cross-coupling of two sp2-hybridized organohalides, featuring high cross-selectivity when the two coupling partners are used in a 1:1 ratio. The high chemoselectivity is governed by the bathocuproine ligand. Moreover, the mild reductive reaction conditions allow that a wide range of functional groups are compatible in this Ullmann cross-coupling.
Funder
National Natural Science Foundation of China
Fundamental Research Funds for the Central Universities