Affiliation:
1. Karolinska Institute, Department of Biosciences at Neo
Abstract
Pyridine reacts readily with P4S10 to form a reagent with the composition C10H10N2P2S5 that is useful for thionations of amides. The thionating properties of this reagent are compared with those of Lawesson’s reagent.1 Introduction2 Development of C10H10N2P2S5
3 Use of Thionation for Modification of Biologically Active Compounds3.1 Thionations of Peptides3.2 Thionated Compounds of Interest as Potential Antivirals3.3 Thionations of Thalidomide and Related Molecules4 Comparison of Lawesson’s Reagent and C10H10N2P2S5
Subject
Organic Chemistry,Catalysis
Cited by
6 articles.
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