Radical Allylation: E-Selective Radical Conjugate Addition–Elimination Reaction from Morita–Baylis–Hillman Adducts

Abstract

Triethylborane-mediated radical allylation was performed from Morita–Baylis–Hillman alcohols with no need of protecting group. The radical conjugated addition–elimination reaction is highly selective, and trisubstituted E-alkenes were obtained. This reaction opened a new route for the preparation of functionalized α,β-unsaturated ketones.