Affiliation:
1. Department of Chemistry, Indian Institute of Technology
Abstract
Palladium-catalyzed copper-free Sonogashira coupling of 2-bromocarbonyls is presented. This method afforded the 2-alkynylaryl carbonyls, useful synthons for the accomplishment of many carbocyclic and heterocyclic motifs. Significantly, the strategy was extended to the one-pot synthesis of isobenzofurans via reduction followed by intramolecular 5-exo-dig cyclization.
Funder
Council of Scientific and Industrial Research (CSIR), New Delhi
Subject
Organic Chemistry,Catalysis
Cited by
8 articles.
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