Affiliation:
1. Taras Shevchenko National University of Kyiv
2. Enamine Ltd.
Abstract
An approach to 3-oxa-7-azabicyclo[3.3.0]octanes, bicyclic morpholine analogues, is reported, which relies on [3+2] cycloaddition of maleic anhydrides or furan-2(5H)-ones and an in situ generated azomethine ylide. The utility of the method was demonstrated on a multigram scale.
Subject
Organic Chemistry,Catalysis
Cited by
6 articles.
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