Palladium-Catalyzed Synthesis of Aryl Nitriles: Using α-Imino­nitrile as Cyano Source for Aryl Halide Cyanations

Abstract

An efficient and ligand-free palladium-catalyzed exchange reaction to synthesize aryl nitriles by using α-iminonitrile as a starting reagent has been developed. This methodology provides an optional method for the synthesis of aryl nitriles with moderate to good yields. At the same time, this approach is adaptable for many substrates.