Mechanochemical Organic Synthesis: The Art of Making Chemistry Green

Abstract

Despite growing interest in mechanochemistry, its application in the organic-synthesis laboratory has still not reached the level of being commonplace. Inspired by this apparent underrepresentation of mechanochemical practice in the broad organic-chemistry community, this article aims to highlight some of the most interesting aspects of modern mechanosynthesis, with particular emphasis on the potential of mechanochemistry to allow reaction discovery and the development of novel synthetic approaches.