Metal-Free Mild Synthesis of Novel 1′H-Spiro[Cycloalkyl-1,2′-quinazolin]-4′(3′H)-ones by an Organocatalytic Cascade Reaction-Reference-Cited by-同舟云学术

Metal-Free Mild Synthesis of Novel 1′H-Spiro[Cycloalkyl-1,2′-quinazolin]-4′(3′H)-ones by an Organocatalytic Cascade Reaction

Published:2017-09-26 Issue:02 Volume:29 Page:203-208
ISSN:0936-5214
Container-title:Synlett
language:en
Short-container-title:Synlett

Author:

Ramesh Rathinam¹,Kalisamy Periyathambi¹,Malecki Jan²,Lalitha Appaswami¹

Affiliation:

1. Department of Chemistry, Periyar University

2. Department of Crystallography, University of Silesia

Abstract

A concise organocatalytic method for the facile synthesis of some novel 1′H-spiro[cycloalkyl-1,2′-quinazolin]-4′(3′H)-ones via a one-pot, three-component condensation of isatoic anhydride, aryl or aliphatic amines and a cyclic ketone is described.

Publisher

Georg Thieme Verlag KG

Subject

Organic Chemistry

Link

http://www.thieme-connect.de/products/ejournals/pdf/10.1055/s-0036-1590917.pdf

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