Author:
Pihko Petri,Mäkinen Mari,Mallik Rosy,Siitonen Juha,Kärki Katja
Abstract
A route to the oxabicyclic cores of the HIV cytoprotective quinolone alkaloids, waltheriones C and D, is described. The approach relies on a stereospecific transannular bromoetherification followed by reductive debromination. The route can also be rendered enantioselective via enzymatic reduction of a key intermediate (>99:1 er).
Cited by
6 articles.
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