Total Synthesis of Luteoalbusin A and Formal Synthesis of T988 C

Abstract

An efficient total synthesis of luteoalbusin A was achieved in nine linear steps and in 17% overall yield from the known and easily accessible 3a-(3-indolyl)-hexahydropyrrolo[2,3-b]indole. A formal synthesis of (+)-T988 C through manipulation of the key intermediate is also reported.