Ultrasound-Accelerated Amide Coupling Reactions Directed toward the Synthesis of 1-Acetyl-3-carboxamide-β-carboline Derivatives of Biological Importance-Reference-Cited by-同舟云学术

Ultrasound-Accelerated Amide Coupling Reactions Directed toward the Synthesis of 1-Acetyl-3-carboxamide-β-carboline Derivatives of Biological Importance

Published:2017-03 Issue:01 Volume:01 Page:0008-0010
ISSN:2509-9396
Container-title:SynOpen
language:en
Short-container-title:SynOpen

Author:

Sharma N.¹,Kumari P.¹,Sharma P.¹,Bhagat N.²,Bhagat S.¹

Affiliation:

1. Organic Synthesis research Laboratory, Department of Chemistry, A.R.S.D. College, University of Delhi

2. Instrumentation & Control Engineering, Netaji Subash Institute of Technology, University of Delhi

Abstract

Several biologically important 1-acetyl-3-carboxamide-β-carboline derivatives were rapidly synthesized by ultrasound-promoted amide coupling of 1-acetyl-9H-pyrido[3,4-b]indole-3-carboxylic acid with substituted aromatic amines. The major advantages of the proposed method are that use of ultrasound irradiations afforded the desired products in a drastically reduced reaction time and in excellent yields compared with conventional stirring.

Publisher

Georg Thieme Verlag KG

Subject

Organic Chemistry,Materials Science (miscellaneous),Biomaterials,Catalysis

Link

http://www.thieme-connect.de/products/ejournals/pdf/10.1055/s-0036-1588167.pdf

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