A Mild and Efficient Method for the Syntheses and Regioselective Ring-Opening of Aziridines-Reference-Cited by-同舟云学术

A Mild and Efficient Method for the Syntheses and Regioselective Ring-Opening of Aziridines

Published:2017-03 Issue:01 Volume:01 Page:0015-0023
ISSN:2509-9396
Container-title:SynOpen
language:en
Short-container-title:SynOpen

Author:

Ghosal Nirnita¹,Mahato Sachinta¹,Chatterjee Rana¹,Santra Sougata²,Zyryanov Grigory²³,Majee Adinath¹

Affiliation:

1. Department of Chemistry, Visva-Bharati (A Central University)

2. Department of Organic and Biomolecular Chemistry, Chemical Engineering Institute, Ural Federal University

3. Institute of Organic Synthesis, Ural Division of the Russian Academy of Sciences

Abstract

We have developed a new synthetic method for the synthesis of aziridines using Chloramine-T as an effective reagent in the presence of NH2OH·HCl and NaIO4. We found that the same combination of NH2OH·HCl and NaIO4 is also very effective for nucleophilic ring opening of aziridines.

Publisher

Georg Thieme Verlag KG

Subject

Organic Chemistry,Materials Science (miscellaneous),Biomaterials,Catalysis

Link

http://www.thieme-connect.de/products/ejournals/pdf/10.1055/s-0036-1588809.pdf

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