Synthesis of N-Substituted 2-Amino-3,4-diiodofurans from Allenes via NIS-Mediated Intramolecular Electrophilic Iodocyclization-Reference-Cited by-同舟云学术

Synthesis of N-Substituted 2-Amino-3,4-diiodofurans from Allenes via NIS-Mediated Intramolecular Electrophilic Iodocyclization

Published:2017-04-20 Issue:13 Volume:49 Page:2917-2927
ISSN:0039-7881
Container-title:Synthesis
language:en
Short-container-title:Synthesis

Author:

Du Yunfei¹²,Li Guangchen¹,Zhang-Negrerie Daisy²

Affiliation:

1. Tianjin Key Laboratory for Modern Drug Delivery & High-Efficiency, School of Pharmaceutical Science and Technology, Tianjin University

2. Collaborative Innovation Center of Chemical Science and Engineering (Tianjin)

Abstract

A facile and efficient method for the syntheses of N-substituted 2-amino-3,4-diiodofurans from various readily available allenic amides has been developed. The reaction was postulated to proceed via an NIS-mediated electrophilic iodocyclization pathway.

Funder

National Natural Science Foundation of China

National Basic Research Project

Tianjin Research Program of Application Foundation and Advanced Technology

Publisher

Georg Thieme Verlag KG

Subject

Organic Chemistry,Catalysis

Link

http://www.thieme-connect.de/products/ejournals/pdf/10.1055/s-0036-1588792.pdf

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