Iodine-Mediated Sulfenylation of Imidazo[1,2-a]pyridines with Ethyl Arylsulfinates-Reference-Cited by-同舟云学术

Iodine-Mediated Sulfenylation of Imidazo[1,2-a]pyridines with Ethyl Arylsulfinates

Published:2021-02-20 Issue:10 Volume:32 Page:1014-1018
ISSN:0936-5214
Container-title:Synlett
language:en
Short-container-title:Synlett

Author:

Tang Dong¹²,Sun Jian¹,Mu Yangxiu¹,Iqbal Zafar¹,Hou Jing¹,Yang Minghua²,Yang Zhixiang¹

Affiliation:

1. Ningxia Center of Agricultural Organic Synthesis, Agricultural Resource and Environment Institute of Ningxia Academy of Agriculture and Forestry Science

2. Department of Chemistry, Lishui University

Abstract

AbstractA simple iodine-mediated approach is reported for the synthesis of sulfenylated imidazo[1,2-a]pyridines through the reaction of imidazo[1,2-a]pyridines with ethyl arylsulfinates under mild conditions. The reaction scope was investigated, and a plausible mechanism is proposed to elucidate the reaction process and activation mode. The results indicate that ethyl sulfinates are efficient sulfur sources for the construction of C–S bonds.

Funder

Natural Science Foundation of Zhejiang Province

Key Research and Development Program of Ningxia

Publisher

Georg Thieme Verlag KG

Subject

Organic Chemistry

Link

http://www.thieme-connect.de/products/ejournals/pdf/10.1055/a-1396-5933.pdf

Reference9 articles.

1. Iodine–triphenylphosphine mediated sulfenylation of imidazoheterocycles with sodium sulfinates

2. Catalyst-Free Regioselective Sulfenylation of Imidazoheterocycles with Sulfonyl Hydrazides in Water