Classic Light Transmission Platelet Aggregometry: Do We Still Need it?

Author:

Gebetsberger Jennifer1,Prüller Florian2

Affiliation:

1. Department of Pediatrics I, Medical University of Innsbruck, Innsbruck, Austria

2. Clinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University of Graz, Graz, Austria

Abstract

AbstractFor more than 50 years, light transmission aggregometry has been accepted as the gold standard test for diagnosing inherited platelet disorders in platelet-rich plasma, although there are other functional approaches performed in whole blood. In this article, several advantages and disadvantages of this technique over other laboratory approaches are discussed in the view of recent guidelines, and the necessity of functional assays, such as light transmission aggregometry in the era of molecular genetic testing, is highlighted.

Publisher

Georg Thieme Verlag KG

Subject

Hematology

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