Current Pharmacological Trends on Myricetin

Author:

Gupta Gudiya1,Siddiqui Mohd Aftab1,Khan Mohd Muazzam1,Ajmal Mohd1,Ahsan Rabiya1,Rahaman Md Azizur2,Ahmad Md Afroz1,Arshad Md3,Khushtar Mohammad1

Affiliation:

1. Department of Pharmacology, Faculty of Pharmacy, Integral University, Lucknow, India

2. Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Integral University, Lucknow, India

3. Department of Zoology, Aligarh Muslim University, Aligarh, India

Abstract

AbstractMyricetin is a member of the group of flavonoids called flavonols. Myricetin is obtained from various fruit, vegetables, tea, berries and red wine. Myricetin is characterized by the pysrogallol B-ring, and the more hydroxylated structure is known to be capable for its increased biological properties compared with other flavonols. Myricetin is produced by the Myricaceae, Anacardiaceae, Polygonaceae, Pinaceae and Primulacea families. It is soluble in organic solvent such as ethanol, DMSO (dimethyl sulfoxide), and dimethyl formamide (DMF). It is sparingly soluble in aqueous buffers. Myricetin shows its various pharmacological activities including antioxidant, anti-amyloidogenic, antibacterial, antiviral, antidiabetic, anticancer, anti-inflammatory, anti-epileptic and anti-ulcer. This review article focuses on pharmacological effects of Myricetin on different diseases such as osteoporotic disorder, anti-inflammatory disorder, alzheimer’s disease, anti-epileptic, cancer, cardiac disorder, diabetic metabolic disorder, hepatoprotective disorder and gastro protective disorder.

Publisher

Georg Thieme Verlag KG

Subject

Drug Discovery,General Medicine

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