NLR as a Prognostic Tool in Orthopaedic Surgery in Elderly Extra-Articular Hip Fracture: A Significant Increase in NLR 24 Hours after Surgical Intervention-Reference-Cited by-同舟云学术

NLR as a Prognostic Tool in Orthopaedic Surgery in Elderly Extra-Articular Hip Fracture: A Significant Increase in NLR 24 Hours after Surgical Intervention

Published:2022-09 Issue:03 Volume:06 Page:136-142
ISSN:2472-8446
Container-title:The Journal of Hip Surgery
language:en
Short-container-title:The Journal of Hip Surgery

Author:

Tomaino Laura¹,Pansieri Simone²,Vigna Luisella³,La Vecchia Carlo⁴,Da Lio Lidia⁵,Moroncini Gianluca⁶,Gigante Antonio Pompilio²

Affiliation:

1. Emergency Medicine Residency Program, Marche Polytechnic University, Ancona, Italy

2. Clinical Orthopaedics, Department of Clinical and Molecular Sciences, Università Politecnica delle Marche, Ancona, Italy

3. Department of Preventive Medicine, Occupational Health Unit “L. Devoto,” Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, Milan, Italy

4. Department of Clinical and Community Sciences (DISSCO), Università degli Studi di Milano, Italy

5. Laboratory Medicine, Azienda Ospedaliera Universitaria Ospedali Riuniti, Marche Polytechnic University, Ancona, Italy

6. Clinica Medica, Azienda Ospedaliera Universitaria Ospedali Riuniti, Marche Polytechnic University, Ancona, Italy

Abstract

AbstractNeutrophil-to-lymphocyte ratio (NLR) was developed as a diagnostic and prognostic tool in many medical conditions, and its use is spreading as a predictor of postoperative outcome in orthopaedic surgery. The aim of this study is to investigate the improvement of NLR 24 hours after surgical intervention in a cohort of 91 patients (F/M = 68/23) with hip fracture who underwent femur intramedullary fixation. Patients were 84.7 ± 7.9 years old, and the mean hospital stay was 13.4 ± 4.7 days, with a mean delay to surgery of 1.9 ± 1.4 days. A significant increase in NLR between baseline (T0) and 24 hours after surgical intervention (T1) was observed in the study sample overall and on subgroup analysis by gender. Nevertheless, no significant effect of NLR on the length of hospital stay was observed.

Publisher

Georg Thieme Verlag KG

Subject

General Earth and Planetary Sciences,General Environmental Science

Link

http://www.thieme-connect.de/products/ejournals/pdf/10.1055/s-0042-1756278.pdf

Reference29 articles.

1. Prediction of postoperative mortality in elderly patient with hip fractures: a single-centre, retrospective cohort study;R Niessen;BMC Anesthesiol,2018

2. Prognostic factors affecting survival of patients with intertrochanteric femoral fractures over 90 years treated with proximal femoral nailing;ÖN Ergin;Eur J Trauma Emerg Surg,2020

3. The neutrophil to lymphocyte ratio on admission and short-term outcomes in orthogeriatric patients;A Fisher;Int J Med Sci,2016

4. Admission neutrophil-to-lymphocyte ratio and postoperative mortality in elderly patients with hip fracture;A Temiz;Ulus Travma Acil Cerrahi Derg,2019

5. Association between increased neutrophil-to-lymphocyte ratio and postoperative delirium in elderly patients with total hip arthroplasty for hip fracture;R He;BMC Psychiatry,2020