Case of Conus Paraganglioma: Case Report with Review

Author:

Sharma Vikas1,Dua Sanjeev2,Ambastha Rooma3

Affiliation:

1. Department of Neurosurgery, Park AMRC Hospital, Mansarovar, Jaipur India

2. Department of Neurosurgery, Max Hospital, Patparganj, Delhi, India

3. Department of Pathology, Max Hospital, Patparganj, Delhi, India

Abstract

AbstractParagangliomas of spine are rare neuroendocrine tumors. They are World Health Organization grade 1 tumors with common location in cauda equina and filum terminale. We report a case of conus paraganglioma. A 57-year-old lady was admitted with low back pain with radiculopathy without bowel and bladder complaints. Magnetic resonance imaging (MRI) lumbosacral spine showed well-defined round-to-oval extramedullary lesion isointense on T1 and hyperintense on T2-weighted images at the level of L1 vertebra (suggestive of) neurogenic tumor. Intraoperatively reddish-brown capsulated tumor arising from conus with extension to filum and compressing the nerve roots was seen. Gross total excision of tumor was done. Microscopic examination showed well-encapsulated cellular tumor composed of sheets, anastomosing lobules, and nests of small, oval-to-round cells interspersed with blood vessels with mild nuclear atypia and occasional mitosis. Immunohistochemistry analysis was positive for synaptophysin and chromogranin suggestive of paraganglioma. Postoperative period was uneventful. MRI of dorso-lumbar spine showed no residual tumor. Patient was asymptomatic 5 months after surgery. The clinical, radiological, and pathological features of this rare tumor entity is presented.

Publisher

Georg Thieme Verlag KG

Subject

Materials Chemistry

Reference13 articles.

1. Secretory ependymoma of the filum terminale;C A Miller;Acta Neuropathol,1970

2. Combined paraganglioma and glioma of conus medullaris and cauda equina;S Shuangshoti;J Surg Oncol,1984

3. Paraganglioma of cauda equina: report of seven cases;N G Singh;Brain Tumor Pathol,2005

4. Functional paraganglioma: a rare conus-cauda lesion;V Agrawal;J Surg Tech Case Rep,2012

5. An unusual case of conus nonfunctioning paraganglioma;B D Diyora;J Spinal Surg,2015

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3