Nucleotide Sequence Sharing between the Human Genome and Primers for Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Detection

Author:

Kanduc Darja1ORCID

Affiliation:

1. Department of Biosciences, Biotechnologies, and Biopharmaceutics, University of Bari, Bari, Italy

Abstract

AbstractThis study shows that oligonucleotide sequences are shared between the human genome and primers that have been proposed/used for SARS-CoV-2 detection by polymerase chain reaction (PCR). The high level of sharing (namely, up to 19mer with a maximum number of gaps equal to 2) might bear implications for the diagnostic validity of SARS-CoV-2 detection by PCR.

Publisher

Georg Thieme Verlag KG

Subject

Literature and Literary Theory,History,Cultural Studies

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1. SARS-CoV-2: The Self-Nonself Issue and Diagnostic Tests;Journal of Laboratory Physicians;2022-07-26

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