Brain Abscess Caused by Eikenella corrodens in an Immunocompetent Child: Case Report and Literature Review

Author:

Karaaslan Ayse1ORCID,Çetin Ceren1,Altıntaş Alara2,Süslü Hikmet Turan3,Akin Yasemin4

Affiliation:

1. Department of Pediatric Infectious Diseases, University of Health Sciences, Kartal Dr Lutfi Kırdar City Hospital, Istanbul, Turkey

2. Koc University School of Medicine, Istanbul, Turkey

3. Department of Neurosurgery, University of Health Sciences, Kartal Dr Lutfi Kirdar City Hospital, Istanbul, Turkey

4. Department of Pediatrics, University of Health Sciences, Kartal Dr Lutfi Kırdar City Hospital, Istanbul, Turkey

Abstract

Abstract Objective Eikenella corrodens is a slow-growing, fastidious, non-motile, facultative anaerobic, Gram-negative bacillus that is commonly found in the human oropharynx. Although many cases have been reported in the adult population, only few cases of brain abscesses caused by E.corrodens have been reported in children so far. Methods Here, we reported the case of a 29-month-old female with complaints of weakness in the right leg twice in the past 3 weeks. Imaging studies revealed a brain abscess in the left parietofrontal lobe. The patient underwent surgery for abscess drainage, microbiological samples were obtained and empirical antibiotic treatment was started. Abscess culture showed the growth of E.corrodens. The bacteria were found to be sensitive to ceftriaxone; hence, the therapy was continued for 46 days with ceftriaxone. A final computed tomography showed the resolution of the abscess. The patient's clinical condition improved and she was discharged without any sequelae. Conclusion Brain abscess should be considered when patients present with neurological deficits. As far as we know, there are only six reported cases of brain abscesses only due to E.corrodens in the pediatric population. Since it is a slow-growing pathogen, early diagnosis and treatment are crucial for patient survival. This case supports the combination of surgical drainage and antibiotics for treatment.

Publisher

Georg Thieme Verlag KG

Subject

Infectious Diseases,Pediatrics, Perinatology and Child Health

Reference14 articles.

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3. Clinical characteristics and outcome of brain abscess: systematic review and meta-analysis;M C Brouwer;Neurology,2014

4. Eikenella corrodens, cause of a vulvar abscess in a diabetic adult;N Oztoprak;Infect Dis Obstet Gynecol,2009

5. Eikenella corrodens infections in children and adolescents: case reports and review of the literature;K Paul;Clin Infect Dis,2001

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