Author:
Zhang Feng-Lian,Wang Yi-Feng,Liu Nan-Nan,Wan Xuan-Chen,Hui Li-Wen
Abstract
AbstractDeoxygenative alkylation of benzyl alcohols was realized by using acetate as the alcohol activation group. The C–O bond homolysis is achieved by a boryl radical-promoted β-scission process. The strategy is amenable to a variety of benzyl alcohols, including primary, secondary, and more challenging tertiary alcohols. The synthetic practicability was demonstrated by a gram-scale one-pot reaction.
Funder
National Natural Science Foundation of China
Natural Science Foundation of Anhui Province
Fundamental Research Funds for the Central Universities
Subject
Organic Chemistry,Catalysis