Understanding protein losing enteropathy (PLE)

Abstract

Protein losing enteropathy (PLE) is not a diagnosis of a specific disease but can be considered a symptom or syndrome of a disease or disorder, often from gastrointestinal origin. Although more common in dogs, it can also be presented in cats, with variation in symptoms being mild to severe and life-threatening. Often requiring hospitalisation, veterinary nurses may become very involved in the care of patients with PLE. Understanding the syndrome and nursing requirements may improve patient recovery. This article discusses the fundamental pathophysiology, aetiology, presentation, diagnostics, treatment and nursing considerations relevant to PLE.