Antiarrhythmic drugs. Part 1: an overview

Abstract

Antiarrhythmic drugs are a broad class of medicines with a variety of indications, mechanisms and unique features. Some are widely used because of their relatively benign nature, while others require careful supervision because of a greater potential for adverse effects. In this first article in a three-part series, we examine the mechanisms that underpin antiarrhythmic drug therapy, discuss classification, and identify commonly used drugs. Important principles for the use of this type of drug are also identified. The importance of careful patient selection, assessment and monitoring are emphasised, as well as the implications of drug choice.