Safety, tolerability and efficacy of incobotulinumtoxinA for the long-term treatment of upper facial lines

Abstract

Aesthetics procedures have increased in popularity over the last few years and have grown to be increasingly affordable to the general population. This literature review aims to explore the efficacy, tolerability, and safety of IncobotulintoxinA in the long-term treating facial lines in response to concerns regarding the effects of repeated treatments with the most currently used formulations in the market. Using the PubMed and CINAHL databases, a review of two prospective studies has been conducted. Results show that IncobotulintoxinA has less concentration of proteins in its formula, leading to less risk of developing neutralizing antibodies down the line with repeated injections. Methodological limitations of the two studies are also discussed.